AKR1A1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human liver cancer tissue, hela cells and human fetal kidney tissue IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 312-324 amino acids of human aldo-keto reductase family 1, member A1 (aldehyde reductase)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	37 kDa
Gene Name	aldo-keto reductase family 1, member A1 (aldehyde reductase)
Database Link	NP_001189342 Entrez Gene 58810 MouseEntrez Gene 78959 RatEntrez Gene 10327 Human UniProt ID P14550
Background	This gene encodes a member of the aldo/keto reductase superfamily; which consists of more than 40 known enzymes and proteins. This member; also known as aldehyde reductase; is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist; all encoding the same protein.
Synonyms	ALDR1; ALR; ARM; DD3; HEL-S-6
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways

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