Nebulin (NEB) Rabbit Polyclonal Antibody

CAT#: TA324106

Anti-NEB Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 50-200
Positive control: Human lung cancer
Predicted cell location: Cytoplasm
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 118-132 amino acids of human nebulin
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name nebulin
Background This gene encodes nebulin; a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates; nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-; species-;and developmental stage-specific. Of the 183 exons in the nebulin gene; at least 43 are alternatively spliced; although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin; the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.
Synonyms NEB177D; NEM2
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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