Cadherin like 23 (CDH23) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 250 amino acids of human cadherin-related 23
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cadherin-related 23
Database Link	NP_443068 Entrez Gene 22295 MouseEntrez Gene 114102 RatEntrez Gene 64072 Human UniProt ID Q9H251
Background	This gene is a member of the cadherin superfamily; whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
Synonyms	CDHR23; USH1D
Reference Data
Protein Families	Transmembrane

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