FAM3A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse pancreas tissue, Human cerebella tissue lysates IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Secreted
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 34-230 amino acids of human amily with sequence similarity 3, member Aamily with sequence similarity 3, member A
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25 kDa
Gene Name	family with sequence similarity 3 member A
Database Link	NP_001164603 Entrez Gene 66294 MouseEntrez Gene 60343 Human UniProt ID P98173
Background	A novel cytokine-like gene family using structure-based methods to search for novel four-helix-bundle cytokines in genomics databases. There are four genes in this family; FAM3A; FAM3B; FAM3C; and FAM3D; each encoding a protein (224-235 amino acids) with a hydrophobic leader sequence. Northern analysis indicates that FAM3B is highly expressed in pancreas; FAM3D in placenta; and FAM3A and FAM3C in almost all tissues. Immunohistochemistry showed that FAM3A is expressed prominently in the vascular endothelium; particularly capillaries.?Fam3a staining in capillary endothelium and endocardium of heart; as well as vascular endothelial staining in many other tissues.
Synonyms	2.19; DLD; DXS560S; XAP-7
Reference Data
Protein Families	Secreted Protein, Transmembrane

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