Galectin 3 (LGALS3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: 231, A375, Hela, HT-29 and A549 cell IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: cytoplasm or nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26 kDa
Gene Name	lectin, galactoside binding soluble 3
Database Link	NP_001170859 Entrez Gene 3958 Human UniProt ID P17931
Background	This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix; the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis; innate immunity; cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
Synonyms	CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
Reference Data
Protein Families	Secreted Protein

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