SLC8A3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 33-47 amino acids of Human solute carrier family 8 (sodium/calcium exchanger), member 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	solute carrier family 8 member A3
Database Link	NP_891978 Entrez Gene 6547 Human UniProt ID P57103
Background	This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes; where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
Synonyms	Ca(2+)-exchange protein 3; Ca2+ exchanger 3; calcium exchan; calcium exchanger SLC8A3; member 3; Na(+); Na+; NCX3; OTTHUMP00000179116; sodium; sodium-calcium exchanger form 3; solute carrier family 8 (sodium; solute carrier family 8 (sodium-calcium exchanger)
Reference Data
Protein Families	Transmembrane
Protein Pathways	Calcium signaling pathway

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