STXBP2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: A549 cells, human liver cancer tissue and Hela cells IHC: 25-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 250 amino acids of human syntaxin binding protein 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	66 kDa
Gene Name	syntaxin binding protein 2
Database Link	NP_001120868 Entrez Gene 20911 MouseEntrez Gene 81804 RatEntrez Gene 6813 Human UniProt ID Q15833
Background	This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking; control of SNARE (soluble NSF attachment protein receptor) complex assembly; and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Synonyms	FHL5; Hunc18b; MUNC18-2; pp10122; UNC18-2; UNC18B
Reference Data
Protein Families	Stem cell - Pluripotency

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