Cyclin A1 (CCNA1) Rabbit Polyclonal Antibody

CAT#: TA323776

Anti-CCNA1 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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经常一起买 (3)
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Recombinant protein of human cyclin A1 (CCNA1), transcript variant 1, 20 µg
    • 20 ug

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Transient overexpression lysate of cyclin A1 (CCNA1), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: 293T cell lysate
IHC: 50-100
Positive control: Human breast cancer
Predicted cell location: Nucleus
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to C terminal 300 amino acids of human cyclin A1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 52 kDa
Gene Name cyclin A1
Background The protein encoded by this gene belongs to the highly conserved cyclin family; whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain; as well as in several leukemic cell lines; and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases; which give two distinct kinase activities; one appearing in S phase; the other in G2; and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators; such as Rb family proteins; transcription factor E2F-1; and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms CT146
Reference Data
Protein Families Druggable Genome
Protein Pathways Acute myeloid leukemia, Cell cycle, Pathways in cancer, Progesterone-mediated oocyte maturation
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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