Aquaporin 2 (AQP2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 100-300 Positive control: Human liver cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 255-271 amino acids of Human Aquaporin-2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	aquaporin 2
Database Link	NP_000477 Entrez Gene 11827 MouseEntrez Gene 25386 RatEntrez Gene 359 Human UniProt ID P41181
Background	The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes; but when it is needed vasopressin binds to the cell surface vasopressin receptor; activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.
Synonyms	AQP-CD; WCH-CD
Reference Data
Protein Families	Druggable Genome, Transmembrane

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