ADH1B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Raji cell lysate IHC: 50-300 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 226-338 amino acids of human alcohol dehydrogenase 1B (class I), beta polypeptide
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	40 kDa
Gene Name	alcohol dehydrogenase 1B (class I), beta polypeptide
Database Link	NP_000659 Entrez Gene 125 Human UniProt ID P00325
Background	The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates; including ethanol; retinol; other aliphatic alcohols; hydroxysteroids; and lipid peroxidation products. This encoded protein; consisting of several homo- and heterodimers of alpha; beta; and gamma subunits; exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha; beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
Synonyms	ADH2; HEL-S-117
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism

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