GCSF Receptor (CSF3R) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human lung cancer Predicted cell location: Cytoplasm, Cell membrane
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 470-484 amino acids of human colony stimulating factor 3 receptor (granulocyte)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	colony stimulating factor 3 receptor
Database Link	NP_000751 Entrez Gene 1441 Human UniProt ID Q99062
Background	The protein encoded by this gene is the receptor for colony stimulating factor 3; a cytokine that controls the production; differentiation; and function of granulocytes. The encoded protein; which is a member of the family of cytokine receptors; may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome; also known as severe congenital neutropenia.
Synonyms	CD114; GCSFR
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer

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