RBMS3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Human liver cancer tissue IHC: 50-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 425-437 amino acids of Human RNA binding motif, single stranded interacting protein 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	48 kDa
Gene Name	RNA binding motif single stranded interacting protein 3
Database Link	NP_001003793 Entrez Gene 207181 MouseEntrez Gene 27303 Human UniProt ID Q6XE24
Background	This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs; RNP1 and RNP2; originally described in RNA binding proteins; and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication; gene transcription; cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism; rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms	FLJ36544
Reference Data

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