Prostate Specific Antigen (KLK3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human cervical cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to N terminal 258 amino acids of Human Kallikrein-3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	kallikrein related peptidase 3
Database Link	NP_001639 Entrez Gene 354 Human UniProt ID P07288
Background	KLK3 is a member of the kallikrein-related peptidase family secreted by the epithelial cells of the prostate gland and lead to the liquefaction of the seminal coagulum. It is thought to function normally in the liquefaction of seminal coagulum; presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein; called PSA in the clinical setting; is useful in the diagnosis and monitoring of prostatic carcinoma.
Synonyms	APS; hK3; KLK2A1; PSA
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein
Protein Pathways	Pathways in cancer, Prostate cancer

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