IL18BP Rabbit Polyclonal Antibody
CAT#: TA323375S
Anti-IL18BP Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: MCF-7 cell lysate IHC: 50-100 Positive control: Human prostate cancer Predicted cell location: Cytoplasm |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 31-195 of Human Interleukin-18-binding protein |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | interleukin 18 binding protein |
Database Link | |
Background | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine; IL18. It binds IL18; prevents the binding of IL18 to its receptor; and thus inhibits IL18-induced IFN-gamma production; resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Synonyms | IL18BPa; interleukin 18 binding protein; MC51L-53L-54L homolog gene product; OTTHUMP00000179141; OTTHUMP00000179143; tadekinig-alfa |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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