Acrosin (ACR) Rabbit Polyclonal Antibody
CAT#: TA323227S
Anti-ACR Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
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CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 500-2000 WB positive control: Human breast cancer tissue lysate |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 407-421 amino acids of human acrosin |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 46 kDa |
Gene Name | acrosin |
Database Link | |
Background | Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form; proacrosin. The active enzyme functions in the lysis of the zona pellucida; thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. |
Synonyms | acrosin; preproacrosin; proacrosin |
Reference Data | |
Protein Families | Druggable Genome, Protease |
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