Endothelin 2 (EDN2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 25-178 amino acids of human endothelin 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	endothelin 2
Database Link	NP_001947 Entrez Gene 1907 Human UniProt ID P20800
Background	Endothelin 2; also known as ET-2; is a protein that in humans is encoded by the EDN2 gene. This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes; such as hypertension and ovulation.?
Synonyms	ET-2; ET2; PPET2
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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