KCNA5 Rabbit Polyclonal Antibody

CAT#: TA323044S

Anti-KCNA5 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Transient overexpression lysate of potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5)
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Applications WB
Recommend Dilution WB: 500-2000
WB positive control: Mouse spleen tissue
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 517-613 amino acids of human potassium voltage-gated channel, shaker-related subfamily, member 5
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 44 kDa
Gene Name potassium voltage-gated channel subfamily A member 5
Background Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release; heart rate; insulin secretion; neuronal excitability; epithelial electrolyte transport; smooth muscle contraction; and cell volume. Four sequence-related potassium channel genes - shaker; shaw; shab; and shal - have been identified in Drosophila; and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel; voltage-gated; shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class; the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless; and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).?
Synonyms ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1
Reference Data
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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