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MASPIN (SERPINB5) Rabbit Polyclonal Antibody
CAT＃: TA322981S
Anti-SERPINB5 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Mouse lung tissue IHC: 100-300 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 42 kDa |
| Gene Name | serpin family B member 5 |
| Database Link | |
| Background | Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth; invasion; and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins; it exhibits no serine protease inhibitory activity. |
| Synonyms | maspin; PI5 |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | p53 signaling pathway |
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SERPINB5 Rabbit Polyclonal Antibody
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