S100A4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Rat lung tissue lysate IHC: 50-300 Positive control: Human cervical cancer Predicted cell location: Cytoplasm, Nucleus, Cell membrane
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 3-15 amino acids of human S100 calcium binding protein A4
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	12 kDa
Gene Name	S100 calcium binding protein A4
Database Link	NP_002952 Entrez Gene 24615 RatEntrez Gene 6275 Human UniProt ID P26447
Background	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells; and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility; invasion; and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants; encoding the same protein; have been identified.
Synonyms	18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98
Reference Data

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