Urocortin (UCN) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 110-124 amino acids of human urocortin
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	urocortin
Database Link	NP_003344 Entrez Gene 22226 MouseEntrez Gene 29151 RatEntrez Gene 7349 Human UniProt ID P55089
Background	This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity; the product of this gene has no sequence similarity to urotensin II.
Synonyms	UI; UROC
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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