ADAM12 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-50 Positive control: Human tonsil Predicted cell location: Secreted
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 223-239 amino acids of human ADAM metallopeptidase domain 12
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ADAM metallopeptidase domain 12
Database Link	NP_003465 Entrez Gene 11489 MouseEntrez Gene 8038 Human UniProt ID O43184
Background	This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins; and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions; including fertilization; muscle development; and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
Synonyms	ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein, Transmembrane

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