IL18R1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: HL60 cell lysate IHC: 50-200 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 25-330 amino acids of human interleukin 18 receptor 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	62 kDa
Gene Name	interleukin 18 receptor 1
Database Link	NP_003846 Entrez Gene 8809 Human UniProt ID Q13478
Background	The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18); and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family; including IL1R2; IL1R1; ILRL2 (IL-1Rrp2); and IL1RL1 (T1/ST2); form a gene cluster on chromosome 2q.
Synonyms	CD218a; CDw218a; IL-1Rrp; IL1RRP; IL18RA
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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