alpha Defensin 1 (DEFA1) Rabbit Polyclonal Antibody
CAT#: TA322800S
Anti-DEFA1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 10-50 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Full length fusion protein |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | defensin alpha 1 |
Database Link | |
Background | Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine; respiratory tract; urinary tract; and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene; defensin; alpha 1; is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin; alpha 3 by only one amino acid. This gene and the gene encoding defensin; alpha 3 are both subject to copy number variation.? |
Synonyms | DEF1; DEFA2; HNP-1; HP-1; HP1; MRS |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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