SLC9A3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 397-411 amino acids of Human solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	solute carrier family 9 member A3
Database Link	NP_004165 Entrez Gene 24784 RatEntrez Gene 105243 MouseEntrez Gene 6550 Human UniProt ID P48764
Background	Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.Binds SLC9A3R1 and SLC9A3R2. Interacts with CHP1; CHP2 and SHANK2. Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels
Synonyms	NHE3
Reference Data
Protein Families	Druggable Genome, Transmembrane

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