RAB35 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 121-135 amino acids of Human Ras-related protein Rab-35
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	RAB35, member RAS oncogene family
Database Link	NP_006852 Entrez Gene 77407 MouseEntrez Gene 288700 RatEntrez Gene 11021 Human UniProt ID Q15286
Background	This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. Rab35 plays an important role in insulin-stimulated GLUT4 translocation in adipocytes.It is the target of TBC1D10A–C and that the intracellular accumulation of endosomal vesicles and impairs exosome secretion were occured when inhibition of Rab35 function.The surface of oligodendroglia in a GTP-dependent manner was localized Rab35; it increases the density of vesicles; and may have a function in docking or tethering.
Synonyms	H-ray; RAB1C; RAY
Reference Data
Protein Families	Druggable Genome

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