CDC37 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Hela cells IHC: 15-50 Positive control: Human breast cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 345-360 amino acids of human cell division cycle 37 homolog (S. cerevisiae)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	44 kDa
Gene Name	cell division cycle 37
Database Link	NP_008996 Entrez Gene 12539 MouseEntrez Gene 114562 RatEntrez Gene 11140 Human UniProt ID Q16543
Background	The protein encoded by this gene is highly similar to Cdc 37; a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4; CDK6; SRC; RAF-1; MOK; as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Synonyms	P50CDC37
Reference Data

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