Aquaporin 0 (MIP) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 20-100 Positive control: Human colorectal cancer Predicted cell location: Cell membrane
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 250-263 amino acids of Human Aquaporin-0
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	28 kDa
Gene Name	major intrinsic protein of lens fiber
Database Link	NP_036196 Entrez Gene 17339 MouseEntrez Gene 25480 RatEntrez Gene 4284 Human UniProt ID P30301
Background	Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined; yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2; AQP5; and AQP6; in a potential gene cluster at 12q13.
Synonyms	AQP0; CTRCT15; LIM1; MIP26; MP26
Reference Data
Protein Families	Druggable Genome, Transmembrane

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