AKAP8L Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela cells and mouse brain tissue IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Nucleus, Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide peptide corresponding to a region derived from 627-640 amino acids of human A kinase (PRKA) anchor protein 8-like
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72 kDa
Gene Name	A-kinase anchoring protein 8 like
Database Link	NP_055186 Entrez Gene 54194 MouseEntrez Gene 26993 Human UniProt ID Q9ULX6
Background	A-kinase anchor protein 8-like is an enzyme that in humans is encoded by the AKAP8L gene. AKAP8L has been shown to interact with Thymopoietin[4][5] and DHX9. Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.
Synonyms	HA95; HAP95; NAKAP; NAKAP95
Reference Data
Protein Families	Druggable Genome

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