ACAD8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 250 amino acids of human acyl-CoA dehydrogenase family, member 8
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	acyl-CoA dehydrogenase family member 8
Database Link	NP_055199 Entrez Gene 66948 MouseEntrez Gene 367196 RatEntrez Gene 27034 Human UniProt ID Q9UKU7
Background	This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.
Synonyms	ACAD-8; ARC42
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Metabolic pathways, Valine, leucine and isoleucine degradation

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