AASDHPPT Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human fetal brain tissue IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36 kDa
Gene Name	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Database Link	NP_056238 Entrez Gene 67618 MouseEntrez Gene 300328 RatEntrez Gene 60496 Human UniProt ID Q9NRN7
Background	The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5; which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
Synonyms	AASD-PPT; CGI-80; LYS2; LYS5
Reference Data
Protein Pathways	Lysine biosynthesis, Lysine degradation, Metabolic pathways

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