Ceramide synthase 2 (CERS2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse skin tissue lysate IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 100-114 amino acids of human ceramide synthase 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45 kDa
Gene Name	ceramide synthase 2
Database Link	NP_071358 Entrez Gene 76893 MouseEntrez Gene 29956 Human UniProt ID Q96G23
Background	This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis. Expressed in kidney; liver; brain; heart; placenta and lung.
Synonyms	L3; LASS2; SP260; TMSG1
Reference Data
Protein Families	Transcription Factors, Transmembrane

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