MURF1 (TRIM63) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Rat skeletal muscle tissue lysate IHC: 50-200 Positive control: Human colorectal cancer Predicted cell location: Nucleus
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide peptide corresponding to a region derived from 2-14 amino acids of human tripartite motif containing 63, E3 ubiquitin protein ligase
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	40 kDa
Gene Name	tripartite motif containing 63
Database Link	NP_115977 Entrez Gene 140939 RatEntrez Gene 84676 Human UniProt ID Q969Q1
Background	This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins; myosin light chain; myosin binding protein; and for muscle-type creatine kinase.
Synonyms	IRF; MURF1; MURF2; RNF28; SMRZ
Reference Data

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