PIWIL4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 546-838 amino acids of human piwi-like RNA-mediated gene silencing 4
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	piwi like RNA-mediated gene silencing 4
Database Link	NP_689644 Entrez Gene 330890 MouseEntrez Gene 689972 RatEntrez Gene 143689 Human UniProt ID Q7Z3Z4
Background	PIWIL4 belongs to the Argonaute family of proteins; which function in development and maintenance of germline stem cells.It plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization; which is essential for the germline integrity.May be involved in the chromatin-modifying pathway by inducing 'Lys-9' methylation of histone H3 at some loci.
Synonyms	HIWI2; MIWI2
Reference Data
Protein Pathways	Dorso-ventral axis formation

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