B7H4 (VTCN1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 81-95 amino acids of human V-set domain containing T cell activation inhibitor 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	V-set domain containing T cell activation inhibitor 1
Database Link	NP_078902 Entrez Gene 242122 MouseEntrez Gene 295322 RatEntrez Gene 79679 Human UniProt ID Q7Z7D3
Background	This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	B7-H4; B7h.5; B7H4; B7S1; B7X; PRO1291; VCTN1
Reference Data
Protein Families	Transmembrane

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