Relaxin 3 receptor 1 (RXFP3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 456-468 amino acids of human relaxin/insulin-like family peptide receptor 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	relaxin/insulin like family peptide receptor 3
Database Link	NP_057652 Entrez Gene 239336 MouseEntrez Gene 51289 Human UniProt ID Q9NSD7
Background	Relaxin-3 is a highly conserved neuropeptide in vertebrate species and binds to the Class A G protein-coupled receptor (GPCR) RXFP3. Relaxin-3 is involved in a wide range of behaviors and targeting of RXFP3 may be relevant for a range of neurological diseases. RXFP3; confirmed that acute and chronic activation of RXFP3 increased feeding and weight gain; and produced changes in plasma leptin and insulin.
Synonyms	GPCR135; RLN3R1; RXFPR3; SALPR
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane

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