LAMP3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Jurkat and Hela cell lysates IHC: 50-100 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 51-66 amino acids of Human lysosomal-associated membrane protein 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	44 kDa
Gene Name	lysosomal associated membrane protein 3
Database Link	NP_055213 Entrez Gene 27074 Human UniProt ID Q9UQV4
Background	Lysosome-associated membrane glycoprotein 3 is a protein that in humans is encoded by the LAMP3 gene. LAMP3 has also recently been designated CD208. Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses .May play a role in dendritic cell function and in adaptive immunity.
Synonyms	CD208; DC-LAMP; DC LAMP; DCLAMP; LAMP; LAMP-3; TSC403
Reference Data
Protein Families	Transmembrane
Protein Pathways	Lysosome

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