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RAMP2 Rabbit Polyclonal Antibody
CAT＃: TA321729S
Anti-RAMP2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: 231 cells |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 71-84 amino acids of Human receptor (G protein-coupled) activity modifying protein 2 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 20 kDa |
| Gene Name | receptor activity modifying protein 2 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins; called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR; a receptor with seven transmembrane domains; can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor; depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein; CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. |
| Synonyms | RAMP2 |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Vascular smooth muscle contraction |
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