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MCSF Receptor (CSF1R) Rabbit Polyclonal Antibody
CAT＃: TA321690S
Anti-CSF1R Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 25-100 Positive control: Human lung cancer Predicted cell location: cytoplasm, Nucleus |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 955-971 amino acids of human colony stimulating factor 1 receptor |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | colony stimulating factor 1 receptor |
| Database Link | |
| Background | The protein encoded by this gene is the receptor for colony stimulating factor 1; a cytokine which controls the production; differentiation; and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. |
| Synonyms | C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Pathways in cancer |
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