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Transglutaminase 2 (TGM2) Rabbit Polyclonal Antibody
CAT＃: TA321660S
Anti-TGM2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Lovo and hela cells, human liver cancer and fetal liver tissue IHC: 15-50 Positive control: Human cervical cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 250 amino acids of human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 77 kDa |
| Gene Name | transglutaminase 2 |
| Database Link | |
| Background | Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved; they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer; is induced by retinoic acid; and appears to be involved in apoptosis. Finally; the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Huntington's disease |
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