Ornithine Decarboxylase (ODC1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 300 amino acids of human ornithine decarboxylase 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ornithine decarboxylase 1
Database Link	NP_002530 Entrez Gene 18263 MouseEntrez Gene 24609 RatEntrez Gene 4953 Human UniProt ID P11926
Background	This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7; the gene encoding this enzyme has been determined to be located on 2p25; with a pseudogene located on 7q31-qter.
Synonyms	ODC
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways

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