BMP3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Human hepatocellsular carcinoma tissue IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 23-42 amino acids of Human Bone morphogenetic protein 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54 kDa
Gene Name	bone morphogenetic protein 3
Database Link	NP_001192 Entrez Gene 651 Human UniProt ID P12645
Background	The protein encoded by this gene is a member of the transforming growth factor beta superfamily. Bone morphogenic protein; also known as osteogenin; induces bone formation. It like other bone morphogenetic proteins (BMP's) is known for its ability to induce bone and cartilage development. It is a disulfide-linked homodimer. It negatively regulates bone density. BMP3 is an antagonist to other BMP's in the differentiation of osteogenic progenitors.It is highly expressed in fractured tissues.
Synonyms	BMP-3A
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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