BMP3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 363-472 amino acids of human bone morphogenetic protein 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	bone morphogenetic protein 3
Database Link	NP_001192 Entrez Gene 25667 RatEntrez Gene 110075 MouseEntrez Gene 651 Human UniProt ID P12645
Background	BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Expressed in adult and fetal cartilage. Highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts.
Synonyms	BMP-3A
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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