Annexin V (ANXA5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse eyes and heart, Human cervical cancer tissue, OP9 and RAW264.7 cells IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 49-263 amino acids of human annexin A5
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36 kDa
Gene Name	annexin A5
Database Link	NP_001145 Entrez Gene 11747 MouseEntrez Gene 25673 RatEntrez Gene 308 Human UniProt ID P08758
Background	The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction; inflammation; growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I; vascular anticoagulant-alpha; endonexin II; lipocortin V; placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons; and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
Synonyms	ANX5; ENX2; HEL-S-7; PP4; RPRGL3
Reference Data

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