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Estrogen Receptor 1 (ESR1) Rabbit Polyclonal Antibody
CAT＃: TA321068S
Anti-ESR1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 100-300 Positive control: Human brain Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 247-261 amino acids of Human estrogen receptor 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | estrogen receptor 1 |
| Database Link | |
| Background | This gene encodes an estrogen receptor; a ligand-activated transcription factor composed of several domains important for hormone binding; DNA binding; and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function; but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer; endometrial cancer; and osteoporosis. Alternative splicing results in several transcript variants; which differ in their 5' UTRs and use different promoters. |
| Synonyms | ER; Era; ESR; ESRA; ESTRR; NR3A1 |
| Reference Data | |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
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