Epoxide hydrolase (EPHX1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colorectal cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 106-455 amino acids of Human Epoxide hydrolase 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	epoxide hydrolase 1
Database Link	NP_000111 Entrez Gene 13849 MouseEntrez Gene 25315 RatEntrez Gene 2052 Human UniProt ID P07099
Background	Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of exogenous chemicals such as polycyclic aromatic hydrocarbons. Mutations in this gene cause preeclampsia; epoxide hydrolase deficiency or increased epoxide hydrolase activity.
Synonyms	EPHX; EPOX; HYL1; MEH
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Metabolism of xenobiotics by cytochrome P450

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