RASSF10 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	RASSF10 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human RASSF10.
Formulation	RASSF10 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	RASSF10 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	Ras association domain family member 10
Database Link	NP_001073990 Entrez Gene 644943 Human UniProt ID A6NK89
Background	RASSF10 Antibody: RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.
Synonyms	AF-6) domain family (N-terminal) member 10; peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor-like; Ras association (RalGDS
Reference Data

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