NETO1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	NETO1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human NETO1.
Formulation	NETO1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	NETO1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	neuropilin and tolloid like 1
Database Link	NP_694821 Entrez Gene 246317 MouseEntrez Gene 307206 RatEntrez Gene 81832 Human UniProt ID Q8TDF5
Background	NETO1 Antibody: Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
Synonyms	BCTL1; BTCL1; neuropilin (NRP) and tolloid (TLL)-like 1; neuropilin- and tolloid-like protein 1; OTTHUMP00000163732
Reference Data
Protein Families	Druggable Genome, Transmembrane

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