CXXC5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CXXC5 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CXXC5.
Formulation	CXXC5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	CXXC5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CXXC finger protein 5
Database Link	NP_057547 Entrez Gene 67393 MouseEntrez Gene 291670 RatEntrez Gene 51523 Human UniProt ID Q7LFL8
Background	CXXC5 Antibody: CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.
Synonyms	CF5; HSPC195; RINF; WID
Reference Data

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