ANKRD25 (KANK2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KANK2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human KANK2 .
Formulation	KANK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	KANK2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 95 kDa; Observed: 102 kDa
Gene Name	KN motif and ankyrin repeat domains 2
Database Link	NP_056308 Entrez Gene 235041 MouseEntrez Gene 100361376 RatEntrez Gene 25959 Human UniProt ID Q63ZY3
Background	KANK2 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK2 (KN motif and ankyrin repeat domain-containing protein 2), was initially identified as a steroid receptor coactivator (SRC) interacting protein (SIP) that could sequester steroid receptor coactivators in the cytoplasm. More recent experiments have shown that while KANK2 is widely expressed, in kidney podocytes, KANK2 localizes to foot processes, suggesting that KANK2 may contribute to controlling actin dynamics in podocyte foot processes.
Synonyms	ANKRD25; MXRA3; PPKWH; SIP
Reference Data

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