ANKRD15 (KANK1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1 .
Formulation	KANK1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	KANK1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Predicted Protein Size	Predicted: 149 kDa; Observed: 150 kDa
Gene Name	KN motif and ankyrin repeat domains 1
Database Link	NP_055973 Entrez Gene 23189 Human UniProt ID Q14678
Background	KANK1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
Synonyms	ANKRD15; CPSQ2; KANK
Reference Data

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